Why does targeted H1 receptor antagonism maintain relevance in managing allergic dermatoses?
Mebhydrolin is a non-sedating, first-generation aliphatic antihistamine that acts as a selective antagonist at peripheral histamine H1 receptor sites. By competitively blocking histamine binding on smooth muscle cells and vascular endothelium, it mitigates systemic allergic responses such as capillary hyperpermeability, tissue edema, and pruritus. Its therapeutic profile makes it effective in...
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